G12R (p.Gly12Arg) variant of TIGIT (Q495A1)
G12R (p.Gly12Arg) in TIGIT (Q495A1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data and structural context.
G12R (p.Gly12Arg) variant details
- p.Gly12Arg
- cosmic curated COSV10104
- Missense
- Variant Prioritization Score for Impact Estimate 0.421
- REVEL 0.37
- CADD 24.20
- PolyPhen-2 0.87
- SIFT 0.00
- Population evidence available
- Structural context available