G12G (p.Gly12Gly) variant of TIGIT (Q495A1)
G12G (p.Gly12Gly) in TIGIT (Q495A1) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.61 / 1. The record also includes population frequency data, published literature, and structural context.
G12G (p.Gly12Gly) variant details
- p.Gly12Gly
- rs201739271
- gnomAD 3-114294097-G-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.608
- CADD 7.26
- Most common in the 1KG:TSI population (allele frequency 0.0049)
- Structural context available
- Literature evidence available