C4W (p.Cys4Trp) variant of TIGIT (Q495A1)
C4W (p.Cys4Trp) in TIGIT (Q495A1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data, published literature, and structural context.
C4W (p.Cys4Trp) variant details
- p.Cys4Trp
- rs1362806561
- gnomAD 3-114293917-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.166
- CADD 7.20
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 3.1e-06)
- Structural context available
- Literature evidence available