C4R (p.Cys4Arg) variant of TIGIT (Q495A1)
C4R (p.Cys4Arg) in TIGIT (Q495A1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.55 / 1. The record also includes population frequency data, published literature, and structural context.
C4R (p.Cys4Arg) variant details
- p.Cys4Arg
- rs765063281
- gnomAD 3-114293915-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.551
- CADD 3.07
- SIFT 0.07
- Most common in the South Asian population (allele frequency 1.6e-05)
- Structural context available
- Literature evidence available