C4C (p.Cys4Cys) variant of TIGIT (Q495A1)
C4C (p.Cys4Cys) in TIGIT (Q495A1) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data, published literature, and structural context.
C4C (p.Cys4Cys) variant details
- p.Cys4Cys
- gnomAD 3-114293917-T-C
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.198
- CADD 7.51
- Most common in the REMAINING population (allele frequency 3.2e-05)
- Structural context available
- Literature evidence available