A35A (p.Ala35Ala) variant of TIGIT (Q495A1)
A35A (p.Ala35Ala) in TIGIT (Q495A1) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data, published literature, and structural context.
A35A (p.Ala35Ala) variant details
- p.Ala35Ala
- rs2078447951
- gnomAD 3-114295588-A-C
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.123
- CADD 5.93
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available
- Literature evidence available