A19V (p.Ala19Val) variant of TIGIT (Q495A1)
A19V (p.Ala19Val) in TIGIT (Q495A1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data, published literature, and structural context.
A19V (p.Ala19Val) variant details
- p.Ala19Val
- gnomAD 3-114294117-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.12
- REVEL 0.04
- MetaLR 0.07
- MetaSVM -1.03
- CADD 8.90
- PolyPhen-2 0.01
- SIFT 0.43
- Most common in the 1KG:PJL population (allele frequency 0.0052)
- Structural context available
- Literature evidence available