A19G (p.Ala19Gly) variant of TIGIT (Q495A1)
A19G (p.Ala19Gly) in TIGIT (Q495A1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.09 / 1. The record also includes population frequency data and structural context.
A19G (p.Ala19Gly) variant details
- p.Ala19Gly
- TOPMed rs2078438424
- gnomAD rs2078438424
- Missense
- Variant Prioritization Score for Impact Estimate 0.0911
- REVEL 0.03
- CADD 8.53
- PolyPhen-2 0.09
- SIFT 0.14
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available