A16V (p.Ala16Val) variant of TIGIT (Q495A1)
A16V (p.Ala16Val) in TIGIT (Q495A1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data, published literature, and structural context.
A16V (p.Ala16Val) variant details
- p.Ala16Val
- gnomAD 3-114294108-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.198
- REVEL 0.04
- MetaLR 0.14
- MetaSVM -0.98
- CADD 22.40
- PolyPhen-2 0.02
- SIFT 0.02
- Population evidence available
- Structural context available
- Literature evidence available