A16T (p.Ala16Thr) variant of TIGIT (Q495A1)
A16T (p.Ala16Thr) in TIGIT (Q495A1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data, published literature, and structural context.
A16T (p.Ala16Thr) variant details
- p.Ala16Thr
- gnomAD 3-114294107-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.171
- REVEL 0.01
- MetaLR 0.12
- MetaSVM -1.01
- CADD 21.80
- PolyPhen-2 0.01
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available