A16S (p.Ala16Ser) variant of TIGIT (Q495A1)
A16S (p.Ala16Ser) in TIGIT (Q495A1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
A16S (p.Ala16Ser) variant details
- p.Ala16Ser
- ExAC rs777596601
- TOPMed rs777596601
- gnomAD rs777596601
- Missense
- Variant Prioritization Score for Impact Estimate 0.163
- REVEL 0.03
- CADD 20.50
- PolyPhen-2 0.04
- SIFT 0.03
- Most common in the Latino/Admixed American population (allele frequency 2.8e-05)
- Structural context available