A16P (p.Ala16Pro) variant of TIGIT (Q495A1)
A16P (p.Ala16Pro) in TIGIT (Q495A1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
A16P (p.Ala16Pro) variant details
- p.Ala16Pro
- ExAC rs777596601
- TOPMed rs777596601
- gnomAD rs777596601
- Missense
- Variant Prioritization Score for Impact Estimate 0.365
- REVEL 0.35
- CADD 23.40
- PolyPhen-2 0.60
- SIFT 0.00
- Most common in the Finnish in Finland (FIN) population (allele frequency 6.1e-05)
- Structural context available