A16D (p.Ala16Asp) variant of TIGIT (Q495A1)
A16D (p.Ala16Asp) in TIGIT (Q495A1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data, published literature, and structural context.
A16D (p.Ala16Asp) variant details
- p.Ala16Asp
- gnomAD 3-114294108-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.313
- REVEL 0.26
- MetaLR 0.16
- MetaSVM -0.95
- CADD 22.50
- PolyPhen-2 0.42
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available