A10G (p.Ala10Gly) variant of TIGIT (Q495A1)
A10G (p.Ala10Gly) in TIGIT (Q495A1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data, published literature, and structural context.
A10G (p.Ala10Gly) variant details
- p.Ala10Gly
- gnomAD 3-114294090-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.203
- REVEL 0.09
- MetaLR 0.15
- MetaSVM -0.99
- CADD 23.80
- PolyPhen-2 0.72
- SIFT 0.03
- Population evidence available
- Structural context available
- Literature evidence available