A10D (p.Ala10Asp) variant of TIGIT (Q495A1)
A10D (p.Ala10Asp) in TIGIT (Q495A1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
A10D (p.Ala10Asp) variant details
- p.Ala10Asp
- TOPMed rs1161667590
- gnomAD rs1161667590
- Missense
- Variant Prioritization Score for Impact Estimate 0.247
- REVEL 0.18
- CADD 23.80
- PolyPhen-2 0.91
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available