W44R (p.Trp44Arg) variant of TGM1 (P22735)
W44R (p.Trp44Arg) in TGM1 (P22735) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.60 / 1. The record also includes population frequency data and structural context.
W44R (p.Trp44Arg) variant details
- p.Trp44Arg
- TOPMed rs887095058
- gnomAD rs887095058
- Missense
- Variant Prioritization Score for Impact Estimate 0.601
- REVEL 0.58
- CADD 25.80
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available