S85T (p.Ser85Thr) variant of TGM1 (P22735)
S85T (p.Ser85Thr) in TGM1 (P22735) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
S85T (p.Ser85Thr) variant details
- p.Ser85Thr
- TOPMed rs987272366
- gnomAD rs987272366
- Missense
- Variant Prioritization Score for Impact Estimate 0.17
- REVEL 0.16
- CADD 7.51
- PolyPhen-2 0.01
- SIFT 0.60
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available