R93W (p.Arg93Trp) variant of TGM1 (P22735)
R93W (p.Arg93Trp) in TGM1 (P22735) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data and structural context.
R93W (p.Arg93Trp) variant details
- p.Arg93Trp
- ExAC rs757823355
- TOPMed rs757823355
- gnomAD rs757823355
- Missense
- Variant Prioritization Score for Impact Estimate 0.443
- REVEL 0.47
- CADD 22.80
- PolyPhen-2 0.98
- SIFT 0.01
- Most common in the African/African-American population (allele frequency 0.00022)
- Structural context available