R37K (p.Arg37Lys) variant of TGM1 (P22735)
R37K (p.Arg37Lys) in TGM1 (P22735) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
R37K (p.Arg37Lys) variant details
- p.Arg37Lys
- TOPMed rs1344562454
- gnomAD rs1344562454
- Missense
- Variant Prioritization Score for Impact Estimate 0.259
- REVEL 0.15
- CADD 10.30
- PolyPhen-2 0.00
- SIFT 0.40
- Most common in the Latino/Admixed American population (allele frequency 0.00013)
- Structural context available