R142Q (p.Arg142Gln) variant of TGM1 (P22735)

R142Q (p.Arg142Gln) in TGM1 (P22735) is a missense change. Clinical records from ClinVar, EBI, and UniProt describe it as likely pathogenic in the context of Autosomal recessive congenital ichthyosis 1. The record also includes published literature and structural context.

R142Q (p.Arg142Gln) variant details