W17C (p.Trp17Cys) variant of TGFBR2 (TGF-beta receptor type-2)
W17C (p.Trp17Cys) in TGFBR2 (TGF-beta receptor type-2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.62 / 1. The record also includes population frequency data and structural context.
W17C (p.Trp17Cys) variant details
- p.Trp17Cys
- cosmic curated COSV99848
- Missense
- Variant Prioritization Score for Impact Estimate 0.616
- REVEL 0.62
- CADD 31.00
- PolyPhen-2 0.32
- SIFT 0.00
- Population evidence available
- Structural context available