W10G (p.Trp10Gly) variant of TGFBR2 (TGF-beta receptor type-2)
W10G (p.Trp10Gly) in TGFBR2 (TGF-beta receptor type-2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data and structural context.
W10G (p.Trp10Gly) variant details
- p.Trp10Gly
- Ensembl rs2125438688
- Missense
- Variant Prioritization Score for Impact Estimate 0.462
- REVEL 0.41
- CADD 29.70
- PolyPhen-2 0.02
- SIFT 0.01
- Most common in the Finnish in Finland (FIN) population (allele frequency 2e-05)
- Structural context available