T23M (p.Thr23Met) variant of TGFBR2 (TGF-beta receptor type-2)
T23M (p.Thr23Met) in TGFBR2 (TGF-beta receptor type-2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data and structural context.
T23M (p.Thr23Met) variant details
- p.Thr23Met
- cosmic curated COSV55461
- Ensembl rs2125438793
- Missense
- Variant Prioritization Score for Impact Estimate 0.449
- REVEL 0.27
- AlphaMissense 0.12
- MetaLR 0.69
- MetaSVM 0.06
- CADD 25.90
- PolyPhen-2 0.90
- Population evidence available
- Structural context available