P25T (p.Pro25Thr) variant of TGFBR2 (TGF-beta receptor type-2)
P25T (p.Pro25Thr) in TGFBR2 (TGF-beta receptor type-2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data, published literature, and structural context.
P25T (p.Pro25Thr) variant details
- p.Pro25Thr
- gnomAD 3-30606956-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.458
- REVEL 0.35
- CADD 23.30
- PolyPhen-2 0.01
- SIFT 0.14
- Population evidence available
- Structural context available
- Literature evidence available