G4W (p.Gly4Trp) variant of TGFBR2 (TGF-beta receptor type-2)
G4W (p.Gly4Trp) in TGFBR2 (TGF-beta receptor type-2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data, published literature, and structural context.
G4W (p.Gly4Trp) variant details
- p.Gly4Trp
- gnomAD 3-30606893-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.459
- REVEL 0.34
- CADD 25.30
- PolyPhen-2 0.11
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available