G32W (p.Gly32Trp) variant of TERT (Telomerase reverse transcriptase)
G32W (p.Gly32Trp) in TERT (Telomerase reverse transcriptase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.57 / 1. The record also includes population frequency data and structural context.
G32W (p.Gly32Trp) variant details
- p.Gly32Trp
- Ensembl rs2126692230
- Missense
- Variant Prioritization Score for Impact Estimate 0.565
- REVEL 0.52
- MetaLR 0.84
- MetaSVM 0.67
- CADD 23.80
- PolyPhen-2 0.91
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9.7e-07)
- Structural context available