F27Y (p.Phe27Tyr) variant of TERT (Telomerase reverse transcriptase)
F27Y (p.Phe27Tyr) in TERT (Telomerase reverse transcriptase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.53 / 1. The record also includes population frequency data and structural context.
F27Y (p.Phe27Tyr) variant details
- p.Phe27Tyr
- Ensembl rs2126692379
- Missense
- Variant Prioritization Score for Impact Estimate 0.53
- REVEL 0.50
- MetaLR 0.71
- MetaSVM 0.42
- CADD 24.00
- PolyPhen-2 0.81
- SIFT 0.10
- Population evidence available
- Structural context available