S31R (p.Ser31Arg) variant of TCF7L2 (Transcription factor 7-like 2)
S31R (p.Ser31Arg) in TCF7L2 (Transcription factor 7-like 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.60 / 1. The record also includes population frequency data and structural context.
S31R (p.Ser31Arg) variant details
- p.Ser31Arg
- Ensembl rs2134177601
- Missense
- Variant Prioritization Score for Impact Estimate 0.598
- CADD 22.10
- PolyPhen-2 0.07
- SIFT 0.12
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available