S31G (p.Ser31Gly) variant of TCF7L2 (Transcription factor 7-like 2)
S31G (p.Ser31Gly) in TCF7L2 (Transcription factor 7-like 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data and structural context.
S31G (p.Ser31Gly) variant details
- p.Ser31Gly
- cosmic curated COSV10524
- ExAC rs754099726
- TOPMed rs754099726
- gnomAD rs754099726
- Missense
- Variant Prioritization Score for Impact Estimate 0.427
- CADD 23.30
- PolyPhen-2 0.03
- SIFT 0.12
- Most common in the Latino/Admixed American population (allele frequency 6.8e-05)
- Structural context available