N34D (p.Asn34Asp) variant of TCF7L2 (Transcription factor 7-like 2)
N34D (p.Asn34Asp) in TCF7L2 (Transcription factor 7-like 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data and structural context.
N34D (p.Asn34Asp) variant details
- p.Asn34Asp
- ExAC rs746837026
- TOPMed rs746837026
- gnomAD rs746837026
- Missense
- Variant Prioritization Score for Impact Estimate 0.486
- CADD 23.60
- PolyPhen-2 0.20
- SIFT 0.04
- Most common in the South Asian population (allele frequency 8.2e-05)
- Structural context available