N15S (p.Asn15Ser) variant of TCF7L2 (Transcription factor 7-like 2)
N15S (p.Asn15Ser) in TCF7L2 (Transcription factor 7-like 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data and structural context.
N15S (p.Asn15Ser) variant details
- p.Asn15Ser
- 1000Genomes rs1287908784
- TOPMed rs1287908784
- gnomAD rs1287908784
- Missense
- Variant Prioritization Score for Impact Estimate 0.507
- CADD 23.80
- PolyPhen-2 0.99
- SIFT 0.09
- Most common in the 1KG:CHS population (allele frequency 0.0049)
- Structural context available