L18M (p.Leu18Met) variant of TCF7L2 (Transcription factor 7-like 2)
L18M (p.Leu18Met) in TCF7L2 (Transcription factor 7-like 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.59 / 1. The record also includes population frequency data and structural context.
L18M (p.Leu18Met) variant details
- p.Leu18Met
- ExAC rs762639760
- gnomAD rs762639760
- Missense
- Variant Prioritization Score for Impact Estimate 0.585
- CADD 19.50
- PolyPhen-2 0.11
- SIFT 1.00
- Population evidence available
- Structural context available