L12L (p.Leu12Leu) variant of TCF7L2 (Transcription factor 7-like 2)
L12L (p.Leu12Leu) in TCF7L2 (Transcription factor 7-like 2) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.60 / 1. The record also includes population frequency data, published literature, and structural context.
L12L (p.Leu12Leu) variant details
- p.Leu12Leu
- rs2030733334
- gnomAD 10-112950790-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.595
- CADD 19.60
- Most common in the Non-Finnish European population (allele frequency 9.1e-07)
- Structural context available
- Literature evidence available