K22K (p.Lys22Lys) variant of TCF7L2 (Transcription factor 7-like 2)
K22K (p.Lys22Lys) in TCF7L2 (Transcription factor 7-like 2) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data, published literature, and structural context.
K22K (p.Lys22Lys) variant details
- p.Lys22Lys
- rs369358979
- gnomAD 10-112950822-A-G
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.503
- CADD 21.40
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available
- Literature evidence available