G9W (p.Gly9Trp) variant of TCF7L2 (Transcription factor 7-like 2)
G9W (p.Gly9Trp) in TCF7L2 (Transcription factor 7-like 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.78 / 1. The record also includes population frequency data, published literature, and structural context.
G9W (p.Gly9Trp) variant details
- p.Gly9Trp
- gnomAD 10-112950781-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.779
- CADD 29.90
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available
- Literature evidence available