G8V (p.Gly8Val) variant of TCF7L2 (Transcription factor 7-like 2)
G8V (p.Gly8Val) in TCF7L2 (Transcription factor 7-like 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.60 / 1. The record also includes population frequency data, published literature, and structural context.
G8V (p.Gly8Val) variant details
- p.Gly8Val
- gnomAD 10-112950779-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.601
- CADD 28.00
- PolyPhen-2 1.00
- SIFT 0.04
- Population evidence available
- Structural context available
- Literature evidence available