G7C (p.Gly7Cys) variant of TCF7L2 (Transcription factor 7-like 2)
G7C (p.Gly7Cys) in TCF7L2 (Transcription factor 7-like 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.78 / 1. The record also includes population frequency data, published literature, and structural context.
G7C (p.Gly7Cys) variant details
- p.Gly7Cys
- gnomAD 10-112950775-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.78
- CADD 29.70
- PolyPhen-2 1.00
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available