G25D (p.Gly25Asp) variant of TCF7L2 (Transcription factor 7-like 2)
G25D (p.Gly25Asp) in TCF7L2 (Transcription factor 7-like 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.67 / 1. The record also includes population frequency data and structural context.
G25D (p.Gly25Asp) variant details
- p.Gly25Asp
- gnomAD rs2030739506
- Missense
- Variant Prioritization Score for Impact Estimate 0.671
- CADD 28.40
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available