E29V (p.Glu29Val) variant of TCF7L2 (Transcription factor 7-like 2)
E29V (p.Glu29Val) in TCF7L2 (Transcription factor 7-like 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.66 / 1. The record also includes population frequency data, published literature, and structural context.
E29V (p.Glu29Val) variant details
- p.Glu29Val
- gnomAD 10-112950842-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.659
- CADD 31.00
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available