E29D (p.Glu29Asp) variant of TCF7L2 (Transcription factor 7-like 2)
E29D (p.Glu29Asp) in TCF7L2 (Transcription factor 7-like 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data and structural context.
E29D (p.Glu29Asp) variant details
- p.Glu29Asp
- Ensembl rs2134177507
- Missense
- Variant Prioritization Score for Impact Estimate 0.461
- CADD 23.20
- PolyPhen-2 0.52
- SIFT 0.07
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available