E29* (p.Glu29Ter) variant of TCF7L2 (Transcription factor 7-like 2)
E29* (p.Glu29Ter) in TCF7L2 (Transcription factor 7-like 2) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.82 / 1. The record also includes population frequency data, published literature, and structural context.
E29* (p.Glu29Ter) variant details
- p.Glu29Ter
- gnomAD 10-112950841-G-T
- Stop Gained
- Variant Prioritization Score for Impact Estimate 0.823
- CADD 37.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available