E24D (p.Glu24Asp) variant of TCF7L2 (Transcription factor 7-like 2)
E24D (p.Glu24Asp) in TCF7L2 (Transcription factor 7-like 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data and structural context.
E24D (p.Glu24Asp) variant details
- p.Glu24Asp
- Ensembl rs2134177271
- Missense
- Variant Prioritization Score for Impact Estimate 0.468
- CADD 23.80
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available