E17K (p.Glu17Lys) variant of TCF7L2 (Transcription factor 7-like 2)
E17K (p.Glu17Lys) in TCF7L2 (Transcription factor 7-like 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.69 / 1. The record also includes population frequency data and structural context.
E17K (p.Glu17Lys) variant details
- p.Glu17Lys
- cosmic curated COSV60508
- Ensembl rs2134176852
- Missense
- Variant Prioritization Score for Impact Estimate 0.692
- CADD 31.00
- PolyPhen-2 1.00
- SIFT 0.00
- Population evidence available
- Structural context available