D11Y (p.Asp11Tyr) variant of TCF7L2 (Transcription factor 7-like 2)
D11Y (p.Asp11Tyr) in TCF7L2 (Transcription factor 7-like 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.79 / 1. The record also includes population frequency data and structural context.
D11Y (p.Asp11Tyr) variant details
- p.Asp11Tyr
- Ensembl rs2134176504
- Missense
- Variant Prioritization Score for Impact Estimate 0.793
- CADD 29.50
- PolyPhen-2 0.99
- SIFT 0.00
- Population evidence available
- Structural context available