D10E (p.Asp10Glu) variant of TCF7L2 (Transcription factor 7-like 2)
D10E (p.Asp10Glu) in TCF7L2 (Transcription factor 7-like 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
D10E (p.Asp10Glu) variant details
- p.Asp10Glu
- Ensembl rs2134176478
- Missense
- Variant Prioritization Score for Impact Estimate 0.408
- CADD 23.60
- PolyPhen-2 1.00
- SIFT 0.06
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available