Y80C (p.Tyr80Cys) variant of TAS2R5 (Taste receptor type 2 member 5)
Y80C (p.Tyr80Cys) in TAS2R5 (Taste receptor type 2 member 5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
Y80C (p.Tyr80Cys) variant details
- p.Tyr80Cys
- ExAC rs776900780
- TOPMed rs776900780
- gnomAD rs776900780
- Missense
- Variant Prioritization Score for Impact Estimate 0.192
- REVEL 0.20
- ESM-1b 0.00
- AlphaMissense 0.12
- MetaLR 0.01
- MetaSVM -0.88
- CADD 14.50
- Most common in the HGDP:TU population (allele frequency 0.1)
- Structural context available