Y44C (p.Tyr44Cys) variant of TAS2R5 (Taste receptor type 2 member 5)
Y44C (p.Tyr44Cys) in TAS2R5 (Taste receptor type 2 member 5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
Y44C (p.Tyr44Cys) variant details
- p.Tyr44Cys
- ExAC rs776934413
- TOPMed rs776934413
- gnomAD rs776934413
- Missense
- Variant Prioritization Score for Impact Estimate 0.243
- REVEL 0.22
- ESM-1b 0.00
- AlphaMissense 0.15
- MetaLR 0.06
- MetaSVM -1.01
- CADD 16.60
- Most common in the HGDP:BANTUKENYA population (allele frequency 0.15)
- Structural context available