W41R (p.Trp41Arg) variant of TAS2R5 (Taste receptor type 2 member 5)
W41R (p.Trp41Arg) in TAS2R5 (Taste receptor type 2 member 5) is a missense change. Clinical records from ClinVar, EBI, and UniProt describe it as uncertain significance in the context of not specified. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data and structural context.
W41R (p.Trp41Arg) variant details
- p.Trp41Arg
- rs747446102
- ClinGen CA4519224
- ClinVar RCV004109243
- ExAC rs747446102
- Uncertain significance
- not specified
- Missense
- Variant Prioritization Score for Impact Estimate 0.095
- REVEL 0.06
- ESM-1b 0.00
- AlphaMissense 0.16
- MetaLR 0.00
- MetaSVM -0.90
- CADD 0.82
- ClinVar: Uncertain significance (not specified)
- EBI: Variant of uncertain significance
- UniProt: Uncertain significance
- Most common in the 1KG:GIH population (allele frequency 0.02)
- Structural context available