V12M (p.Val12Met) variant of TAS2R5 (Taste receptor type 2 member 5)
V12M (p.Val12Met) in TAS2R5 (Taste receptor type 2 member 5) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
V12M (p.Val12Met) variant details
- p.Val12Met
- NCI-TCGA Cosmic COSV9992
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.144
- REVEL 0.05
- ESM-1b 0.00
- AlphaMissense 0.25
- MetaLR 0.00
- MetaSVM -0.90
- CADD 13.00
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the HGDP:YORUBA population (allele frequency 0.048)
- Structural context available