V12L (p.Val12Leu) variant of TAS2R5 (Taste receptor type 2 member 5)
V12L (p.Val12Leu) in TAS2R5 (Taste receptor type 2 member 5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
V12L (p.Val12Leu) variant details
- p.Val12Leu
- ExAC rs773755643
- TOPMed rs773755643
- gnomAD rs773755643
- Missense
- Variant Prioritization Score for Impact Estimate 0.187
- REVEL 0.14
- ESM-1b 0.00
- AlphaMissense 0.20
- MetaLR 0.00
- MetaSVM -0.94
- CADD 14.90
- Most common in the HGDP:TUSCAN population (allele frequency 0.062)
- Structural context available